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IT is a group of disorders in which some Antibodies are developed which attack the kidney and damage it and cause the kidney function to worsen and also may attack other organs of the body. If untreated they usually are progressive and may lead to CKD. They may present with Protein in urine Blood in urine (may be visible or may be found on urine routine testing) Increased BP Swelling legs Increased creatinine Usually, a kidney biopsy is required for accurate diagnosis and treatment of this condition.